Invention Grant
US09345780B2 Site specific delivery of nucleic acids by combining targeting ligands with endosomolytic components
有权
通过将靶向配体与内体分解组分结合来实现核酸的现场特异性递送
- Patent Title: Site specific delivery of nucleic acids by combining targeting ligands with endosomolytic components
- Patent Title (中): 通过将靶向配体与内体分解组分结合来实现核酸的现场特异性递送
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Application No.: US14043682Application Date: 2013-10-01
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Publication No.: US09345780B2Publication Date: 2016-05-24
- Inventor: Muthiah Manoharan , Kallanthottathil G. Rajeev , David Butler , Muthusamy Jayaraman
- Applicant: Tekmira Pharmaceuticals Corporation
- Applicant Address: CA Burnaby
- Assignee: Tekmira Pharmaceuticals Corporation
- Current Assignee: Tekmira Pharmaceuticals Corporation
- Current Assignee Address: CA Burnaby
- Agency: Viksnins Harris & Padys PLLP
- Main IPC: A61K47/48
- IPC: A61K47/48 ; A61K48/00 ; C12N15/11 ; C12N15/87
Abstract:
The invention relates to compositions and methods for site-specific delivery of nucleic acids by combining them with targeting ligands and endosomolytic components.
Public/Granted literature
- US20140256785A1 SITE SPECIFIC DELIVERY OF NUCLEIC ACIDS BY COMBINING TARGETING LIGANDS WITH ENDOSOMOLYTIC COMPONENTS Public/Granted day:2014-09-11
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