Invention Grant
US09346741B2 Polyamine transport selective therapeutic agents with enhanced stability
有权
多胺转运选择性治疗剂具有增强的稳定性
- Patent Title: Polyamine transport selective therapeutic agents with enhanced stability
- Patent Title (中): 多胺转运选择性治疗剂具有增强的稳定性
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Application No.: US14388856Application Date: 2013-03-14
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Publication No.: US09346741B2Publication Date: 2016-05-24
- Inventor: Otto Phanstiel, IV , Aaron Muth
- Applicant: Otto Phanstiel, IV , Aaron Muth
- Applicant Address: US FL Orlando
- Assignee: University of Central Florida Research Foundation, Inc.
- Current Assignee: University of Central Florida Research Foundation, Inc.
- Current Assignee Address: US FL Orlando
- Agency: Beusse, Wolter, Sanks & Maire, PLLC
- Agent Timothy H. Van Dyke
- International Application: PCT/US2013/031166 WO 20130314
- International Announcement: WO2013/148230 WO 20131003
- Main IPC: C07C211/31
- IPC: C07C211/31 ; A61K31/785 ; C08G73/02 ; A61K31/138 ; C07C211/27 ; C07C211/30
Abstract:
Disclosed herein are di-substituted aryl polyamine compounds and methods of making and using the same. The di-substituted polyamine compounds act as PTS targeting agents, which selectively target the polyamine transport system (PTS) with high efficacy and have improved stability in the presence of amine oxidases.
Public/Granted literature
- US20150017231A1 POLYAMINE TRANSPORT SELECTIVE THERAPEUTIC AGENTS WITH ENHANCED STABILITY Public/Granted day:2015-01-15
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