Invention Grant
US09346751B2 Process for preparing 1, 3-Dihydroimidazole-2-Thione Derivatives
有权
1,3-二氢咪唑-2-硫酮衍生物的制备方法
- Patent Title: Process for preparing 1, 3-Dihydroimidazole-2-Thione Derivatives
- Patent Title (中): 1,3-二氢咪唑-2-硫酮衍生物的制备方法
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Application No.: US14127231Application Date: 2012-06-29
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Publication No.: US09346751B2Publication Date: 2016-05-24
- Inventor: Alexander Beliaev , Jorge Bruno Reis Wahnon , David Alexander Learmonth , Jonathan Madec , Jean-Marie Schneider , William Maton
- Applicant: Alexander Beliaev , Jorge Bruno Reis Wahnon , David Alexander Learmonth , Jonathan Madec , Jean-Marie Schneider , William Maton
- Applicant Address: PT S. Mamede do Coronado
- Assignee: Bial-Portela & CA, S.A.
- Current Assignee: Bial-Portela & CA, S.A.
- Current Assignee Address: PT S. Mamede do Coronado
- Agency: Conley Rose, P.C.
- Agent Rodney B. Carroll
- International Application: PCT/PT2012/000024 WO 20120629
- International Announcement: WO2013/002660 WO 20130103
- Main IPC: C07D405/04
- IPC: C07D405/04 ; C07C311/17 ; C07C311/16 ; C07C235/80
Abstract:
The present invention relates to a process for preparing (R)-5-(2-(benzylamino)ethyl)-1-(6,8-difluorochroman-3-yl)-1H-imidazole-2(3H)-thione, and pharmaceutically acceptable salts thereof, especially the hydrochloride salt. The invention also relates to a process for making intermediates useful in the formation of said compound, and to the intermediates, per se.
Public/Granted literature
- US20140221668A1 Process Public/Granted day:2014-08-07
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