Invention Grant
- Patent Title: Alkyl linked quinolinyl modulators of RORγt
- Patent Title (中): 烷基连接的喹啉基调节剂RORγt
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Application No.: US14513455Application Date: 2014-10-14
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Publication No.: US09346782B2Publication Date: 2016-05-24
- Inventor: Kristi A. Leonard , Kent Barbay , James P. Edwards , Kevin D. Kreutter , David A. Kummer , Umar Maharoof , Rachel Nishimura , Maud Urbanski , Hariharan Venkatesan , Aihua Wang , Ronald L. Wolin , Craig R. Woods , Maxwell D. Cummings
- Applicant: Janssen Pharmaceutica NV
- Applicant Address: BE
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE
- Agent Yuriy P. Stercho
- Main IPC: C07D401/06
- IPC: C07D401/06 ; C07D417/06 ; C07D413/06
Abstract:
The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.
Public/Granted literature
- US20150105369A1 ALKYL LINKED QUINOLINYL MODULATORS OF RORyt Public/Granted day:2015-04-16
Information query
