Invention Grant
- Patent Title: Substituted 4-pyridones and their use as inhibitors of neutrophil elastase activity
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Application No.: US14981999Application Date: 2015-12-29
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Publication No.: US09346794B1Publication Date: 2016-05-24
- Inventor: Thorsten Oost , Dennis Fiegen , Christian Gnamm
- Applicant: Boehringer Ingelheim International GmbH
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Edward S. Lazer
- Priority: EP12181542 20120823
- Main IPC: A61K31/54
- IPC: A61K31/54 ; A61K31/50 ; A61K31/501 ; A61K38/00 ; A61P11/06 ; A61P17/00 ; A61P29/00 ; C07D215/00 ; C07D213/62 ; C07D417/04 ; C07D213/82 ; C07D401/04 ; C07D413/04 ; C07D405/04

Abstract:
This invention relates to substituted 4-pyridones of formula 1 and their use as inhibitors of neutrophil elastase activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of pulmonary, gastrointestinal and genitourinary diseases, inflammatory diseases of the skin and the eye and other auto-immune and allergic disorders, allograft rejection, and oncological diseases.
Public/Granted literature
- US20160130265A1 SUBSTITUTED 4-PYRIDONES AND THEIR USE AS INHIBITORS OF NEUTROPHIL ELASTASE ACTIVITY Public/Granted day:2016-05-12
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