Invention Grant
- Patent Title: Formulations pharmacokinetics of deuterated benzoquinoline inhibitors of vesicular monoamine transporter 2
- Patent Title (中): 荚膜单胺转运蛋白氘代苯并喹啉抑制剂的药代动力学研究
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Application No.: US14030322Application Date: 2013-09-18
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Publication No.: US09346800B2Publication Date: 2016-05-24
- Inventor: Andreas Sommer , Chengzhi Zhang , John Carter , John Arthur , Margaret Bradbury , Thomas Gant , Manouchehr Shahbaz
- Applicant: Auspex Pharmaceuticals, Inc.
- Applicant Address: US CA La Jolla
- Assignee: Auspex Pharmaceuticals, Inc.
- Current Assignee: Auspex Pharmaceuticals, Inc.
- Current Assignee Address: US CA La Jolla
- Agent Dennis A. Bennett; Cynthia Hathaway
- Main IPC: A61K31/473
- IPC: A61K31/473 ; C07D455/06 ; A61K31/4745 ; A61K9/00 ; A61K9/16 ; A61K9/20 ; A61K9/28 ; A61K9/48 ; A61K9/50 ; A61K45/06

Abstract:
The present invention relates to new pharmaceutical compositions comprising benzoquinoline compounds, and methods to inhibit vesicular monoamine transporter 2 (VMAT2) activity in a subject for the treatment of chronic hyperkinetic movement disorders.
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