Invention Grant
US09346820B2 HIV-1 protease inhibitors having gem-di-fluoro bicyclic P2-ligands
有权
具有偕二氟双环P2-配体的HIV-1蛋白酶抑制剂
- Patent Title: HIV-1 protease inhibitors having gem-di-fluoro bicyclic P2-ligands
- Patent Title (中): 具有偕二氟双环P2-配体的HIV-1蛋白酶抑制剂
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Application No.: US14483043Application Date: 2014-09-10
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Publication No.: US09346820B2Publication Date: 2016-05-24
- Inventor: Arun K. Ghosh , Hiroaki Mitsuya , Sofiya Yashchuk
- Applicant: Purdue Research Foundation
- Applicant Address: US IN West Lafayette
- Assignee: Purdue Research Foundation
- Current Assignee: Purdue Research Foundation
- Current Assignee Address: US IN West Lafayette
- Agency: Schwegman Lundberg & Woessner, P.A.
- Main IPC: C07D493/04
- IPC: C07D493/04
Abstract:
Various embodiments of the present invention relate to, among other things, compounds and methods of using those compounds to treat an HIV infection. The compounds of the various embodiments of the present invention provide, among other things, therapeutic agents having enhanced penetration capability across the blood-brain barrier, such that they can enter the CNS to treat an HIV-1 infection in the CNS.
Public/Granted literature
- US20150072958A1 HIV-1 PROTEASE INHIBITORS HAVING GEM-DI-FLUORO BICYCLIC P2-LIGANDS Public/Granted day:2015-03-12
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