Invention Grant
- Patent Title: Non-human mammals for the production of chimeric antibodies
- Patent Title (中): 用于生产嵌合抗体的非人哺乳动物
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Application No.: US13121883Application Date: 2009-09-30
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Publication No.: US09346873B2Publication Date: 2016-05-24
- Inventor: Larry Green , Hiroaki Shizuya
- Applicant: Larry Green , Hiroaki Shizuya
- Applicant Address: US CA Burlingame
- Assignee: Ablexis, LLC
- Current Assignee: Ablexis, LLC
- Current Assignee Address: US CA Burlingame
- Agency: Cooley LLP
- International Application: PCT/US2009/059131 WO 20090930
- International Announcement: WO2010/039900 WO 20100408
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; C12N15/63 ; A01K67/00 ; C07K16/00 ; A01K67/027 ; C12N15/85
Abstract:
The invention provides knock-in non-human cells and mammals having a genome encoding chimeric antibodies and methods of producing knock-in cells and mammals. Certain aspects of the invention include chimeric antibodies, humanized antibodies, pharmaceutical compositions and kits. Certain aspects of the invention also relate to diagnostic and treatment methods using the antibodies of the invention.
Public/Granted literature
- US20110236378A1 NON-HUMAN MAMMALS FOR THE PRODUCTION OF CHIMERIC ANTIBODIES Public/Granted day:2011-09-29
Information query
