Invention Grant
US09346917B2 Method involving 1-benzotriazolyl carbonate esters of poly(ethylene glycol) 有权
涉及聚(乙二醇)的1-苯并三唑基碳酸酯的方法

  • Patent Title: Method involving 1-benzotriazolyl carbonate esters of poly(ethylene glycol)
  • Patent Title (中): 涉及聚(乙二醇)的1-苯并三唑基碳酸酯的方法
  • Application No.: US14467634
    Application Date: 2014-08-25
  • Publication No.: US09346917B2
    Publication Date: 2016-05-24
  • Inventor: Antoni Kozlowski
  • Applicant: NEKTAR THERAPEUTICS
  • Applicant Address: US CA San Francisco
  • Assignee: Nektar Therapeutics
  • Current Assignee: Nektar Therapeutics
  • Current Assignee Address: US CA San Francisco
  • Agent Mark A. Wilson
  • Main IPC: A61K47/00
  • IPC: A61K47/00 C08G65/48 A61K47/48
Method involving 1-benzotriazolyl carbonate esters of poly(ethylene glycol)
Abstract:
The invention provides for preparing a polymer-active agent conjugate, the method comprising the steps of reacting an amino acid derivative with a biologically active agent under conditions to form a polymer-active agent conjugate.
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