Invention Grant
US09347058B2 Methods for the selection of binding proteins 有权
选择结合蛋白的方法

  • Patent Title: Methods for the selection of binding proteins
  • Patent Title (中): 选择结合蛋白的方法
  • Application No.: US14117689
    Application Date: 2012-05-16
  • Publication No.: US09347058B2
    Publication Date: 2016-05-24
  • Inventor: Dasa Lipovsek
  • Applicant: Dasa Lipovsek
  • Applicant Address: US NJ Princeton
  • Assignee: Bristol-Myers Squibb Company
  • Current Assignee: Bristol-Myers Squibb Company
  • Current Assignee Address: US NJ Princeton
  • Agent Isabelle M. Clauss
  • International Application: PCT/US2012/038032 WO 20120516
  • International Announcement: WO2012/158739 WO 20121122
  • Main IPC: C40B30/04
  • IPC: C40B30/04 C12N15/10 G01N33/68
Methods for the selection of binding proteins
Abstract:
This application provides an improved screening method for the selection of target-binding proteins having desirable biophysical properties. The method combines mRNA display and yeast surface display in a way that takes advantage of the desirable attributes of both processes.
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