A quantum interference device includes: a gas cell housing metal atoms; a light emitting unit emitting light to the gas cell; a light receiving unit receiving light penetrating the gas cell; a cell temperature control unit controlling the gas cell temperature; a light emitting unit temperature control unit controlling the light emitting unit temperature; an analog circuit including a light receiving circuit which processes a light receiving signal output from the light receiving unit, and controls an atomic resonance signal; a digital circuit controlling the analog circuit; a first substrate; and a second substrate. The light receiving circuit is provided on the first substrate. At least one of the cell temperature control unit, the light emitting unit temperature control unit, and the digital circuit is provided on the second substrate. The first and second substrates at least partially overlap with each other in a plan view.