A surgical fastener applier is disclosed and includes a handle portion, a tubular member extending from the handle portion and defining a longitudinal axis, a drive member rotatably supported in the tubular member and in the handle portion, and a plurality of fasteners. The drive member is configured to rotate while in a deflected condition with respect to the longitudinal axis. The drive member includes a proximal portion, a central portion, and a distal portion, the central portion being relatively more flexible configuration as compared to at least one of the proximal portion and the distal portion. The plurality of fasteners is disposed within the tubular member and is configured to engage a portion of the drive member such that rotational motion of the drive member causes distal advancement of at least one fastener of the plurality of fasteners through the tubular member.