Invention Grant
- Patent Title: Re-directed immunotherapy
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Application No.: US14660137Application Date: 2015-03-17
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Publication No.: US09358282B2Publication Date: 2016-06-07
- Inventor: Mark Cobbold , David Millar
- Applicant: The University of Birmingham
- Applicant Address: GB Birmingham
- Assignee: The University of Birmingham
- Current Assignee: The University of Birmingham
- Current Assignee Address: GB Birmingham
- Agency: McNeill Baur PLLC
- Priority: GB1104514.3 20110317; GB1203434.4 20120228
- Main IPC: C07K14/005
- IPC: C07K14/005 ; C07K16/28 ; A61K45/06 ; A61K38/20 ; A61K39/395 ; A61K39/245 ; A61K47/48 ; A61K39/12 ; C07K16/32 ; A61K39/08 ; A61K39/145 ; A61K39/235 ; C12N7/00 ; A61K39/00
Abstract:
The invention provides an agent for preventing or treating a condition characterized by the presence of unwanted cells, the agent comprising: (i) a targeting moiety that is capable of targeting to the unwanted cells; and (ii) a T cell antigen, wherein the T cell antigen can be released from the targeting moiety by selective cleavage of a cleavage site in the agent in the vicinity of the unwanted cells.
Public/Granted literature
- US20150250868A1 Re-Directed Immunotherapy Public/Granted day:2015-09-10
Information query
