The invention relates to a composition comprising an aqueous admixture of ceramic particles, polysaccharide, a therapeutic agent and, optionally, a polymer, and methods of using the same. The present invention provides a flowable bone void filler for use in medical situations where bone regeneration is desired. In an exemplary embodiment the bone void filler comprises a polysaccharide, a ceramic material and a polymer that exhibits thermosetting properties such that it exists as a viscous liquid at room temperatures and as a gel at about body temperature. In another exemplary embodiment the bone void filler comprises a polysaccharide, a ceramic material, a polymer that exhibits thermosetting properties such that it exists as a viscous liquid at room temperature and as a gel at about body temperatures, and a therapeutic agent.