Invention Grant
- Patent Title: Non-natural amino acids
- Patent Title (中): 非天然氨基酸
-
Application No.: US13784212Application Date: 2013-03-04
-
Publication No.: US09359291B2Publication Date: 2016-06-07
- Inventor: Thomas A. Dix
- Applicant: MUSC Foundation for Research Development
- Applicant Address: US SC Charleston
- Assignee: MUSC Foundation for Research Development
- Current Assignee: MUSC Foundation for Research Development
- Current Assignee Address: US SC Charleston
- Agency: Saul Ewing LLP
- Agent Kathryn Doyle; Domingos J. Silva
- Main IPC: C07C279/14
- IPC: C07C279/14 ; C07C229/12 ; C07D233/46 ; C07D233/48 ; C07D239/14 ; C07C229/08 ; C07C257/14 ; C07D231/06 ; C07K7/08 ; A61K38/00

Abstract:
This invention relates in one aspect to non-natural desamino alkyl amino acid compounds, methods of making these compounds, and peptides containing these compounds. In one embodiment, the peptide is neurotensin (8-13) in which the N-terminus is an alpha-desamino, alpha-methyl-N,N-dimethyl-homolysine residue of the invention.
Public/Granted literature
- US20130217632A1 Non-Natural Amino Acids Public/Granted day:2013-08-22
Information query