Invention Grant
- Patent Title: Pyrazine kinase inhibitors
- Patent Title (中): 吡嗪激酶抑制剂
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Application No.: US14360178Application Date: 2012-11-23
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Publication No.: US09359308B2Publication Date: 2016-06-07
- Inventor: Yonghong Song , Qing Xu , Zhaozhong J. Jia , Brian Kane , Shawn M. Bauer , Anjali Pandey
- Applicant: Portola Pharmaceuticals, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: PORTOLA PHARMACEUTICALS, INC.
- Current Assignee: PORTOLA PHARMACEUTICALS, INC.
- Current Assignee Address: US CA South San Francisco
- Agency: Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
- International Application: PCT/US2012/066468 WO 20121123
- International Announcement: WO2013/078466 WO 20130530
- Main IPC: C07D401/12
- IPC: C07D401/12 ; C07D403/12 ; C07D417/12 ; A61K31/497 ; C07D241/28 ; C07D401/14 ; C07D403/14 ; C07D405/12 ; C07D405/14 ; C07D409/14 ; C07D413/12 ; C07D413/14 ; C07D495/04 ; C07D417/14 ; C07D471/04 ; C07D513/04
Abstract:
Provided are pyrazine compounds of Formula (I) for inhibiting of Syk kinase, intermediates used in making such compounds, methods for their preparation, pharmaceutical compositions thereof, methods for inhibition Syk kinase activity, and methods for treating conditions mediated at least in part by Syk kinase activity.
Public/Granted literature
- US20140309209A1 Pyrazine Kinase Inhibitors Public/Granted day:2014-10-16
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