Invention Grant
- Patent Title: Substituted piperidines as sodium channel blockers
- Patent Title (中): 取代的哌啶作为钠通道阻断剂
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Application No.: US14468737Application Date: 2014-08-26
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Publication No.: US09359330B2Publication Date: 2016-06-07
- Inventor: Laykea Tafesse , Jae Hyun Park
- Applicant: Purdue Pharma L.P.
- Applicant Address: US CT Stamford
- Assignee: Purdue Pharma L.P.
- Current Assignee: Purdue Pharma L.P.
- Current Assignee Address: US CT Stamford
- Agency: Purdue Pharma L.P.
- Agent Alan L. Koller; Weiying Yang
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D211/60 ; C07D401/10

Abstract:
The present disclosure provides substituted piperidines or pyrrolidines having Formula IA: and the pharmaceutically acceptable salts and solvates thereof, wherein R1, R2a, R2b, R6, A, X, m and n are defined as set forth in the specification. In certain embodiments, Compounds of the present disclosure are useful for treating pain. The present disclosure is also directed to the use of Compounds of the present disclosure to treat a disorder responsive to blockade of one or more sodium channels.
Public/Granted literature
- US20150057300A1 SUBSTITUTED PIPERIDINES AS SODIUM CHANNEL BLOCKERS Public/Granted day:2015-02-26
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