Invention Grant
US09359338B2 Cyclopropanecarboxamido-substitute aromatic compounds as anti-tumor agents
有权
环丙烷甲酰氨基取代芳香族化合物作为抗肿瘤剂
- Patent Title: Cyclopropanecarboxamido-substitute aromatic compounds as anti-tumor agents
- Patent Title (中): 环丙烷甲酰氨基取代芳香族化合物作为抗肿瘤剂
-
Application No.: US14408943Application Date: 2013-06-24
-
Publication No.: US09359338B2Publication Date: 2016-06-07
- Inventor: Deyi Zhang , Ruihao Zhang , Boyu Zhong , Chuan Shih
- Applicant: Crown Bioscience Inc. (Taiwan)
- Applicant Address: TW Xinyi Dist. Taipei
- Assignee: CROWN BIOSCIENCE INC. (Taiwan)
- Current Assignee: CROWN BIOSCIENCE INC. (Taiwan)
- Current Assignee Address: TW Xinyi Dist. Taipei
- Agency: Jun He Law Offices P.C.
- Agent James J. Zhu
- Priority: CN201210213116 20120626; CN201310172393 20130416
- International Application: PCT/CN2013/000731 WO 20130624
- International Announcement: WO2014/000418 WO 20140103
- Main IPC: C07D401/12
- IPC: C07D401/12 ; A61K31/4427 ; C07D413/12 ; A61K31/44 ; C07D403/12 ; A61K31/505 ; A61K31/506 ; C07D213/75 ; C07D239/47 ; C07D213/68 ; C07D213/72 ; C07D405/12
Abstract:
Provided are cyclopropanecarboxamido-substituted aromatic compounds that inhibit protein kinases and their use in anti-tumor area. In particular, tyrosine-kinase inhibitors and Raf-kinase inhibitors as anti-tumor agents, their preparation, pharmaceutical composition, and their use in the treatment of cancer are also provided.
Public/Granted literature
- US20150197511A1 CYCLOPROPANECARBOXAMIDO-SUBSTITUTE AROMATIC COMPOUNDS AS ANTI-TUMOR AGENTS Public/Granted day:2015-07-16
Information query
