Invention Grant
US09359351B2 Cap/endo dual inhibitors and their use in the treatment, amelioration or prevention of a viral disease
有权
Cap / endo双重抑制剂及其在治疗,改善或预防病毒性疾病中的用途
- Patent Title: Cap/endo dual inhibitors and their use in the treatment, amelioration or prevention of a viral disease
- Patent Title (中): Cap / endo双重抑制剂及其在治疗,改善或预防病毒性疾病中的用途
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Application No.: US14793699Application Date: 2015-07-07
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Publication No.: US09359351B2Publication Date: 2016-06-07
- Inventor: Tanja Schulz-Gasch , Robert Weikert , Werner Neidhart , Helmut Buschmann , Oliver Szolar , Andrea Wolkerstorfer , Norbert Handler , Franz-Ferdinand Roch , Stephen Cusack
- Applicant: F. Hoffmann-La Roche AG , Savira pharmaceuticals GmbH , European Molecular Biology Laboratory
- Applicant Address: CH Basel AT Vienna DE Heidelberg
- Assignee: F. Hoffmann-La Roche AG,Savira pharmaceuticals GmbH,European Molecular Biology Laboratory
- Current Assignee: F. Hoffmann-La Roche AG,Savira pharmaceuticals GmbH,European Molecular Biology Laboratory
- Current Assignee Address: CH Basel AT Vienna DE Heidelberg
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K31/4985 ; A61K45/06 ; A61K31/506 ; C07D519/00

Abstract:
The present invention relates to a compound having the general formula (V), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, codrug, cocrystal, prodrug, tautomer, racemate, enantiomer, or diastereomer or mixture thereof, which are useful in treating, ameloriating or preventing a viral disease. Furthermore, specific combination therapies are disclosed.
Public/Granted literature
- US20160002227A1 CAP/ENDO DUAL INHIBITORS AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE Public/Granted day:2016-01-07
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