Invention Grant
- Patent Title: Cyclohexyl azetidine derivatives as JAK inhibitors
- Patent Title (中): 环己基氮杂环丁烷衍生物作为JAK抑制剂
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Application No.: US13588776Application Date: 2012-08-17
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Publication No.: US09359358B2Publication Date: 2016-06-07
- Inventor: James D. Rodgers , Argyrios G. Arvanitis
- Applicant: James D. Rodgers , Argyrios G. Arvanitis
- Applicant Address: US DE Wilmington US DE Wilimington
- Assignee: Incyte Holdings Corporation,Incyte Corporation
- Current Assignee: Incyte Holdings Corporation,Incyte Corporation
- Current Assignee Address: US DE Wilmington US DE Wilimington
- Agency: Fish & Richardson P.C.
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/519 ; A61P35/00 ; A61P35/02 ; C07D473/04
Abstract:
The present invention provides cyclohexyl azetidine derivatives of Formula I: or pharmaceutically acceptable salts thereof, as well as their compositions and methods of use, that modulate the activity of Janus kinase (JAK) and are useful in the treatment of diseases related to the activity of JAK including, for example, inflammatory disorders, autoimmune disorders, cancer, and other diseases.
Public/Granted literature
- US20130045963A1 Cyclohexyl Azetidine Derivatives as JAK Inhibitors Public/Granted day:2013-02-21
Information query
