Invention Grant
- Patent Title: TLR agonists
- Patent Title (中): TLR激动剂
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Application No.: US13682208Application Date: 2012-11-20
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Publication No.: US09359360B2Publication Date: 2016-06-07
- Inventor: Dennis A. Carson , Kenji Takabayashi , Howard B. Cottam , Michael Chan , Christina C. N. Wu
- Applicant: Suzanne Grimshaw
- Applicant Address: US CA Oakland
- Assignee: The Regents of The University of California
- Current Assignee: The Regents of The University of California
- Current Assignee Address: US CA Oakland
- Agency: Schwegman Lundberg & Woessner, P.A.
- Main IPC: A61K31/52
- IPC: A61K31/52 ; A61K31/7076 ; C12P19/40 ; C07D473/16 ; C07D473/34 ; C07D473/18 ; C07D473/24
Abstract:
The present invention provides for TLR agonist conjugates (compounds) and compositions, as well as methods of using them. The compounds of the invention are broad-spectrum, long-lasting, and non-toxic combination of synthetic immunostimulatory agents, which are useful for activating the immune system of a mammal, preferably a human and can help direct the pharmacophore to the receptor within the endosomes of target cells and enhance the signal transduction induced by the pharmacophore.
Public/Granted literature
- US20130165455A1 TLR AGONISTS Public/Granted day:2013-06-27
Information query
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