Invention Grant
US09359366B2 Intermediate of Ticagrelor and preparation method therefor, and preparation method for Ticagrelor 有权
替卡格雷中间体及其制备方法及替卡格雷的制备方法

Intermediate of Ticagrelor and preparation method therefor, and preparation method for Ticagrelor
Abstract:
Disclosed are intermediates of Ticagrelor and a preparation method therefor, and a preparation method for Ticagrelor. Specifically, disclosed is an intermediate, namely, a compound of Formula (VI), for preparing Ticagrelor. Further disclosed is a method for preparing the intermediate and a method for preparing Ticagrelor by using the intermediate. Ticagrelor is prepared by using the intermediate, so that the synthesis process is simple, and a defect that long reaction times under high temperature that are required in the existing methods are avoided. The method is suitable for mass production in industry, energy consumption is reduced, pollution of the environment is reduced, and discharge of waste is reduced.
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