Invention Grant
- Patent Title: Caged ceramide-1-phosphate derivatives
- Patent Title (中): 笼养神经酰胺-1-磷酸酯衍生物
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Application No.: US13504206Application Date: 2010-10-26
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Publication No.: US09359389B2Publication Date: 2016-06-07
- Inventor: Robert Bittman , Antonio Gomez Munoz
- Applicant: Robert Bittman , Antonio Gomez Munoz
- Applicant Address: US NY New York
- Assignee: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
- Current Assignee: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
- Current Assignee Address: US NY New York
- Agency: Hoffmann & Baron, LLP
- International Application: PCT/US2010/054145 WO 20101026
- International Announcement: WO2011/056599 WO 20110512
- Main IPC: C12N5/02
- IPC: C12N5/02 ; C07F9/09 ; A61K31/661 ; C07F9/24 ; C07F9/653 ; C07F9/655
Abstract:
The invention relates to novel caged ceramide 1-phosphate (C1P), caged ceramide 1-phosphate derivatives(C1P), and the method of using them for delivering C1P intracellularly in vitro and in vivo, for research and therapeutic purposes. Therapeutic purposes include treatment of diseases associated with cell death, such as neurodegerative diseases, including Alzheimer's disease. The disclosed compositions may also be used for wound healing.
Public/Granted literature
- US20120238018A1 Caged Ceramide-1-Phosphate Derivatives Public/Granted day:2012-09-20
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