Invention Grant
US09359403B2 Activated collagen scaffold materials and their special fused active restoration factors
有权
活化胶原蛋白支架材料及其特殊的融合活性修复因子
- Patent Title: Activated collagen scaffold materials and their special fused active restoration factors
- Patent Title (中): 活化胶原蛋白支架材料及其特殊的融合活性修复因子
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Application No.: US14320105Application Date: 2014-06-30
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Publication No.: US09359403B2Publication Date: 2016-06-07
- Inventor: Jianwu Dai , Bing Chen , Hang Lin , Wenjie Sun , Wenxue Zhao
- Applicant: YANTAI ZHENGHAI BIO-TECHNOLOGY CO., LTD. , INSTITUTE OF GENETICS AND DEVELOPMENTAL BIOLOGY CHINESE ACADEMY OF SCIENCE
- Applicant Address: CN Yantai, Shandong
- Assignee: YANTAI ZHENGHAI BIO-TECH CO., LTD
- Current Assignee: YANTAI ZHENGHAI BIO-TECH CO., LTD
- Current Assignee Address: CN Yantai, Shandong
- Agency: Knobbe, Martens, Olson & Bear, LLP
- Priority: CN200510132792 20051226; CN200610081506 20060524
- Main IPC: C07K7/06
- IPC: C07K7/06 ; A61L27/22 ; A61L27/24 ; C07K14/48 ; C07K14/485 ; C07K14/49 ; C07K14/50 ; C07K14/51 ; C07K14/52 ; C07K14/78 ; A61K38/00
Abstract:
Provided are activated collagen scaffold materials as well as their special fused active restoration factors useful for promoting tissue repair, such as bone damage repair or nerve injury repair. The special fused active restoration factors are fusion proteins comprising a collagen-binding domain (CBD) at N-/C-terminus of cytokines, wherein the collagen-binding domain is a polypeptide consisting of 7-27 amino acid residues with a conservative sequence shown in SEQ ID NO:12 at N-terminus.
Public/Granted literature
- US20140316109A1 ACTIVATED COLLAGEN SCAFFOLD MATERIALS AND THEIR SPECIAL FUSED ACTIVE RESTORATION FACTORS Public/Granted day:2014-10-23
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