Invention Grant
US09359406B2 Vaccine for a therapeutic or a prophylactic treatment of myasthenia gravis
有权
用于重症肌无力治疗或预防性治疗的疫苗
- Patent Title: Vaccine for a therapeutic or a prophylactic treatment of myasthenia gravis
- Patent Title (中): 用于重症肌无力治疗或预防性治疗的疫苗
-
Application No.: US14086479Application Date: 2013-11-21
-
Publication No.: US09359406B2Publication Date: 2016-06-07
- Inventor: Edwin J. Blalock , Stephane P. Huberty
- Applicant: CuraVac Inc.
- Applicant Address: US DE Wilmington, New Castle
- Assignee: CURAVAC INC.
- Current Assignee: CURAVAC INC.
- Current Assignee Address: US DE Wilmington, New Castle
- Agency: Browdy and Neimark, P.L.L.C.
- Main IPC: C07K7/08
- IPC: C07K7/08 ; C07K14/47 ; C07K14/705 ; A61K38/00 ; A61K39/00
Abstract:
A therapeutic composition comprising (1) a complementary peptide comprising a sequence complementary to a major immunogenic region of an acetylcholine receptor (AChR) involved in myasthenia gravis (MG), the sequence being SEQ ID NO:1 (with modified tryptophan in position 8 carrying at least one 2,4,6-trimethoxybenzyl group as hydrocarbonation), (2) a complementary peptide having at least a sequence SEQ ID NO:2, which is complementary to a T-cell recognition site of the acetylcholine receptor, and (3) at least one carrier, may be used in the therapeutic or prophylactic treatment of myasthenia gravis in mammals.
Public/Granted literature
- US20140161831A1 VACCINE FOR A THERAPEUTIC OR A PROPHYLACTIC TREATMENT OF MYASTHENIA GRAVIS Public/Granted day:2014-06-12
Information query
