Invention Grant
US09359411B2 Yeast expressed classical swine fever virus glycoprotein E2 and use thereof
有权
酵母菌表达经典猪瘟病毒糖蛋白E2及其应用
- Patent Title: Yeast expressed classical swine fever virus glycoprotein E2 and use thereof
- Patent Title (中): 酵母菌表达经典猪瘟病毒糖蛋白E2及其应用
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Application No.: US14106761Application Date: 2013-12-14
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Publication No.: US09359411B2Publication Date: 2016-06-07
- Inventor: Chienjin Huang , Maw-Sheng Chien , Guang-Jan Lin
- Applicant: MAX HSING BIOTECH CO., LTD.
- Applicant Address: TW New Taipei
- Assignee: MAW HSING BIOTECH CO., LTD.
- Current Assignee: MAW HSING BIOTECH CO., LTD.
- Current Assignee Address: TW New Taipei
- Agency: Pai Patent Trademark Law Firm
- Agent Chao-Chang David Pai
- Priority: TW97129117A 20080731
- Main IPC: C12Q1/70
- IPC: C12Q1/70 ; C12P1/00 ; A61K39/12 ; A61K39/42 ; C07K14/005 ; A61K39/00
Abstract:
The present invention provides a recombinant yeast system for expressing the glycoprotein E2 of classical swine fever virus (CSFV), in which the expression level of yE2 is improved by codon optimization and shortening coding region of E2 gene. The truncated E2 subunits are used as major active ingredient in anti-CSFV vaccines and useful diagnostic blocking ELISA kits for CSFV infection with easy manipulation and low cost.
Public/Granted literature
- US20140099338A1 YEAST EXPRESSED CLASSICAL SWINE FEVER VIRUS GLYCOPROTEIN E2 AND USE THEREOF Public/Granted day:2014-04-10
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