Invention Grant
- Patent Title: Fab-glycosylated antibodies
- Patent Title (中): Fab糖基化抗体
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Application No.: US13816390Application Date: 2011-08-10
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Publication No.: US09359439B2Publication Date: 2016-06-07
- Inventor: Steffen Goletz , Antje Danielczyk , Lars Stoeckl
- Applicant: Steffen Goletz , Antje Danielczyk , Lars Stoeckl
- Applicant Address: DE Berlin
- Assignee: Glycotope GmbH
- Current Assignee: Glycotope GmbH
- Current Assignee Address: DE Berlin
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Jane E. Remillard, Esq.; Jill Gorny Sloper, Esq.
- Priority: WOPCT/EP2010/004878 20100810
- International Application: PCT/EP2011/063791 WO 20110810
- International Announcement: WO2012/020065 WO 20120216
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28 ; C07K16/00 ; C07K16/30 ; C07K16/18 ; A61K39/00
Abstract:
The present invention pertains to a method for controlling the circulation half-life of antibodies by adjusting the amount of sialic acid in the carbohydrates attached to the Fab part of the antibodies. Furthermore, the present invention provides antibodies having an increased circulation half-life.
Public/Granted literature
- US20130209458A1 FAB-GLYCOSYLATED ANTIBODIES Public/Granted day:2013-08-15
Information query
