Invention Grant
- Patent Title: Compositions and methods for treating neurological disorders
- Patent Title (中): 用于治疗神经障碍的组合物和方法
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Application No.: US13625597Application Date: 2012-09-24
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Publication No.: US09359445B2Publication Date: 2016-06-07
- Inventor: Steven M. Finkbeiner , Vikram Ramnath Rao , Sarah Rosemary Carter , Eva Suzanne LaDow , Hong Joo Kim , Matthew Campioni
- Applicant: The J. David Gladstone Institutes
- Applicant Address: US CA San Francisco
- Assignee: The J. David Gladstone Institutes
- Current Assignee: The J. David Gladstone Institutes
- Current Assignee Address: US CA San Francisco
- Agency: Bozicevic, Field & Francis LLP
- Agent Michael B. Rubin
- Main IPC: C07K16/40
- IPC: C07K16/40 ; A61K31/7088 ; C12N15/113

Abstract:
The present disclosure provides methods for treating neurological disorders, generally involving modulating protein kinase D1 (PKD1) activity levels in a neuron or glial cell in an individual in need thereof. The present disclosure provides antibodies specific for PKD1. The present disclosure provides a genetically modified non-human mammal deficient in PKD1 activity.
Public/Granted literature
- US20130095113A1 COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISORDERS Public/Granted day:2013-04-18
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