Invention Grant
- Patent Title: Method for differentiation into retinal cells from stem cells
- Patent Title (中): 从干细胞分化成视网膜细胞的方法
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Application No.: US13055709Application Date: 2010-10-06
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Publication No.: US09359592B2Publication Date: 2016-06-07
- Inventor: Sung Sup Park , Ji Yeon Kim
- Applicant: Sung Sup Park , Ji Yeon Kim
- Applicant Address: KR Seoul
- Assignee: SNU R&DB Foundation
- Current Assignee: SNU R&DB Foundation
- Current Assignee Address: KR Seoul
- Priority: KR10-2009-0094854 20091006
- International Application: PCT/KR2010/006832 WO 20101006
- International Announcement: WO2011/043591 WO 20110414
- Main IPC: C12N5/07
- IPC: C12N5/07 ; A61P27/02 ; C12Q1/02 ; A61K35/44 ; C12N5/079

Abstract:
Disclosed is a method for inducing stem cells to differentiate into retinal cells at high yield within a short period of time, without gene implantation and co-culture with retinal tissues, by implementing a differentiation process similar to the in vivo embryonic development in chemically defined conditions. Also, retinal cells including the photoreceptor cells and their progenitor cells, and various types of other retinal cells, generated according to the method, are disclosed. A composition comprising the retinal cells and a method are provided for treating retinal degeneration-related diseases. The differentiated photoreceptor cells, when transplanted into degenerated or injured retinas, can be engrafted and fused within the retinas to prevent or cure retinal degeneration.
Public/Granted literature
- US20110223140A1 METHOD FOR DIFFERENTIATION INTO RETINAL CELLS FROM STEM CELLS Public/Granted day:2011-09-15
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