Invention Grant
US09359596B2 Modified bacteriophage including an alpha/beta small acid-soluble spore protein (SASP) gene
有权
改良的噬菌体包括α/β小酸溶性孢子蛋白（SASP）基因
- Patent Title: Modified bacteriophage including an alpha/beta small acid-soluble spore protein (SASP) gene
- Patent Title (中): 改良的噬菌体包括α/β小酸溶性孢子蛋白（SASP）基因
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Application No.: US14190727Application Date: 2014-02-26
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Publication No.: US09359596B2Publication Date: 2016-06-07
- Inventor: Heather Fairhead , Adam Wilkinson , Sarah Holme , Katy Pitts , Alison Jackson
- Applicant: PHICO THERAPEUTICS LTD.
- Applicant Address: GB Babraham, Cambridge
- Assignee: PHICO THERAPEUTICS LTD.
- Current Assignee: PHICO THERAPEUTICS LTD.
- Current Assignee Address: GB Babraham, Cambridge
- Agency: LeClairRyan, a professional corporation
- Agent Robin L. Teskin
- Main IPC: A01N63/00
- IPC: A01N63/00 ; A01N65/00 ; A61K39/09 ; A61K39/07 ; C12N15/00 ; C07K1/00 ; C12N7/00 ; A61K38/16 ; C07K14/32
Abstract:
Provided is a modified bacteriophage capable of infecting a target bacterium, which bacteriophage includes an α/β small acid-soluble spore protein (SASP) gene encoding a SASP which is toxic to the target bacterium, wherein the SASP gene is under the control of a constitutive promoter which is foreign to the bacteriophage and the SASP gene.
Public/Granted literature
- US20140242032A1 Modified Bacteriophage Including an Alpha/Beta Small Acid-Soluble Spore Protein (SASP) Gene Public/Granted day:2014-08-28
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