Invention Grant
US09359608B2 Modulation of signal transducer and activator of transcription 3 (STAT3) expression
有权
信号转导和转录激活因子3（STAT3）表达的调控
- Patent Title: Modulation of signal transducer and activator of transcription 3 (STAT3) expression
- Patent Title (中): 信号转导和转录激活因子3（STAT3）表达的调控
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Application No.: US14338880Application Date: 2014-07-23
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Publication No.: US09359608B2Publication Date: 2016-06-07
- Inventor: Eric E. Swayze , Susan M. Freier , Robert A. MacLeod , Youngsoo Kim
- Applicant: ISIS PHARMACEUTICALS, INC.
- Applicant Address: US CA Carlsbad
- Assignee: ISIS Pharmaceuticals, Inc.
- Current Assignee: ISIS Pharmaceuticals, Inc.
- Current Assignee Address: US CA Carlsbad
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; C12N15/113 ; C07H21/00 ; C12N15/00 ; C12N15/11
Abstract:
Disclosed herein are antisense compounds and methods for decreasing STAT3 mRNA and protein expression. Such methods, compounds, and compositions are useful to treat, prevent, or ameliorate hyperproliferative diseases.
Public/Granted literature
- US20140336237A1 MODULATION OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 3 (STAT3) EXPRESSION Public/Granted day:2014-11-13
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