The tool holder for use with a ladder is a toolbox adapted for use with a step ladder. The tool holder for use with a ladder is a storage unit that can be securely attached to a ladder to reduce the need to climb up and down the ladder to get required tools. The tool holder for use with a ladder comprises a base structure 101 that further comprises a first container, a second container, one or more pockets, a plurality of clips, a plurality of rings, a first ladder clip and a second ladder clip.