- Patent Title: Twin-focus photothermal correlation spectroscopy method and device for the characterization of dynamical processes in liquids and biomaterials with the help of absorbing markers
-
Application No.: US14232304Application Date: 2012-07-12
-
Publication No.: US09360416B2Publication Date: 2016-06-07
- Inventor: Frank Cichos , Marco Braun , Markus Selmke , Romy Schachoff
- Applicant: Frank Cichos , Marco Braun , Markus Selmke , Romy Schachoff
- Applicant Address: DE Leipzig
- Assignee: Universität Leipzig
- Current Assignee: Universität Leipzig
- Current Assignee Address: DE Leipzig
- Agent Gudrun E. Huckett
- Priority: EP11173831 20110713
- International Application: PCT/EP2012/063741 WO 20120712
- International Announcement: WO2013/007804 WO 20130117
- Main IPC: G01N21/00
- IPC: G01N21/00 ; G01N21/31 ; G01N21/17 ; B82Y15/00 ; G01N33/487

Abstract:
The invention relates to a method and a device for twin-focus photothermal correlation spectroscopy for the characterization of dynamical processes in liquids and biomaterials with the help of absorbing markers. Thereby non-fluorescent absorbing nano objects are heated by an intensity-modulated heating laser which leads to a refractive index gradient lens around the object. This refractive index gradient is detected by a detection laser with a focal volume that, depending on the position of the heated object relative to the focal plane of the detection beam, splits into two-sub-volumes forming a twin-focus comprising two sharply separated parts of a focal volume showing no spatial overlap.
Public/Granted literature
Information query