An organic light emitting diode pixel compensation circuit is disclosed. The compensation circuit compensates threshold voltage of a TFT and supply voltage in a pixel circuit to address non-uniform in a display. In the circuit, a first transistor transmits a data signal to a first capacitor based on a scan signal; a second transistor transmits a reference signal to the first capacitor based on a first light emission signal; a third transistor connects a gate of a drive transistor with a drain of the drive transistor based on the scan signal to read the difference between supply voltage and threshold voltage of the drive transistor and to transmit the difference to the first capacitor and a second capacitor; and the drive transistor generates the drive current based on the supply voltage and the voltage on the first capacitor to drive an organic light emitting diode emit light.