The present invention relates to a method and apparatus to objectively measure stress and fatigue using measurement tools, record stress and fatigue related data in a standardized database, create automated prompts and alerts based upon pre-defined stress and fatigue thresholds (which are derived based upon individual end-user and task performance), provide a number of interventions (which can be preferentially selected by the individual end-user), create data-driven best practice guidelines though meta-analysis of the database, and provide an objective tool for comparative technology assessment.