Invention Grant
- Patent Title: SHK-based pharmaceutical compositions and methods of manufacturing and using the same
- Patent Title (中): 基于SHK的药物组合物及其制备和使用方法
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Application No.: US14124669Application Date: 2012-06-05
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Publication No.: US09381261B2Publication Date: 2016-07-05
- Inventor: Shawn P Iadonato , Eric J Tarcha
- Applicant: Shawn P Iadonato , Eric J Tarcha
- Applicant Address: US WA Seattle
- Assignee: Kineta One, LLC
- Current Assignee: Kineta One, LLC
- Current Assignee Address: US WA Seattle
- International Application: PCT/US2012/040857 WO 20120605
- International Announcement: WO2012/170392 WO 20121213
- Main IPC: A61K38/16
- IPC: A61K38/16 ; A61K38/00 ; C07K5/00 ; C07K7/00 ; C07K16/00 ; C07K17/00 ; C07K1/00 ; B01L3/00 ; G01N31/22 ; G01N33/52 ; A61K51/08 ; C07K14/00 ; A61K38/17 ; C07K14/435 ; A61K47/48 ; A61K49/00 ; B01L3/12 ; B01L9/00 ; B01L99/00
Abstract:
Disclosed herein are pharmaceutical compositions having the sequence Arg-Ser-Cys-Ile-Asp-Thr-Ile-Pro-Lys-Ser-Arg-Cys-Thr-Ala-Phe-Gln-Cys-Lys-His-Ser-Xaa-Lys-Tyr-Arg-Leu-Ser-Phe-Cys-Arg-Lys-Thr-Cys-Gly-Thr-Cys (SEQ ID NO: 1). The disclosed compositions can include an acid or amide at the C-terminus of SEQ ID NO: 1 and the polypeptide can be attached to an organic or inorganic chemical entity that has an anionic charge. The polypeptide can be detectably labeled for diagnostic purposes. Methods of manufacturing and using the pharmaceutical compounds are also disclosed.
Public/Granted literature
- US20140221271A1 SHK-BASED PHARMACEUTICAL COMPOSITIONS AND METHODS OF MANUFACTURING AND USING THE SAME Public/Granted day:2014-08-07
Information query
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