Invention Grant
US09382200B2 Process for the preparation of and crystalline forms of optical enantiomers of modafinil
有权
莫达非尼的光学对映异构体的制备和结晶形式的方法
- Patent Title: Process for the preparation of and crystalline forms of optical enantiomers of modafinil
- Patent Title (中): 莫达非尼的光学对映异构体的制备和结晶形式的方法
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Application No.: US12507584Application Date: 2009-07-22
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Publication No.: US09382200B2Publication Date: 2016-07-05
- Inventor: Olivier Neckebrock , Laurent Courvoisier , Stéphanie Graf , Gilles Serrure , Gérard Francois Coquerel , Sébastien Rose , Christine Besselievre , Franck Patrick Mallet , Adriaan Jan Van Langevelde
- Applicant: Olivier Neckebrock , Laurent Courvoisier , Stéphanie Graf , Gilles Serrure , Gérard Francois Coquerel , Sébastien Rose , Christine Besselievre , Franck Patrick Mallet , Adriaan Jan Van Langevelde
- Applicant Address: FR La Defense (Paris)
- Assignee: Teva Sante
- Current Assignee: Teva Sante
- Current Assignee Address: FR La Defense (Paris)
- Priority: FR0216412 20021220
- Main IPC: A61K31/165
- IPC: A61K31/165 ; C07C317/40 ; A61P25/00 ; C07C317/28 ; C07C315/04 ; C07C315/06

Abstract:
The invention relates to a polymorphic form of (−)-modafinil that produces a powder X-ray diffraction spectrum comprising intensity peaks corresponding to interplanar spacings of about 8.54, 4.56, and 3.78 Å, and a process for the preparation thereof.
Public/Granted literature
- US20100022653A1 Process for the Preparation of and Crystalline Forms of Optical Enantiomers of Modafinil Public/Granted day:2010-01-28
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