Invention Grant
US09382208B1 Negative allosteric modulators of metabotropic glutamate receptor 2
有权
代谢型谷氨酸受体2的负变构调节剂
- Patent Title: Negative allosteric modulators of metabotropic glutamate receptor 2
- Patent Title (中): 代谢型谷氨酸受体2的负变构调节剂
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Application No.: US15006486Application Date: 2016-01-26
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Publication No.: US09382208B1Publication Date: 2016-07-05
- Inventor: P. Jeffrey Conn , Craig W. Lindsley , Kyle A. Emmitte , Andrew S. Felts , Katrina A. Bollinger
- Applicant: Vanderbilt University
- Applicant Address: US TN Nashville
- Assignee: Vanderbilt University
- Current Assignee: Vanderbilt University
- Current Assignee Address: US TN Nashville
- Agency: Michael Best & Friedrich LLP
- Main IPC: C07D215/233
- IPC: C07D215/233 ; C07D401/12 ; C07D417/14 ; C07D413/06 ; C07D401/06
Abstract:
Described are negative allosteric modulators of metabotropic glutamate receptor 2 (mGlu2), pharmaceutical compositions including the compounds, and methods of using the compounds and compositions for treating depression, anxiety, obsessive-compulsive disorder, cognitive disorders, Alzheimer's disease, or autism spectrum disorders in a subject.
Public/Granted literature
- US20160214940A1 NEGATIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR 2 Public/Granted day:2016-07-28
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