Invention Grant
US09382228B2 N-acyl-N′-(pyridin-2-yl) ureas and analogs exhibiting anti-cancer and anti-proliferative activities
有权
N-酰基-N' - （吡啶-2-基）脲和表现出抗癌和抗增殖活性的类似物
- Patent Title: N-acyl-N′-(pyridin-2-yl) ureas and analogs exhibiting anti-cancer and anti-proliferative activities
- Patent Title (中): N-酰基-N' - （吡啶-2-基）脲和表现出抗癌和抗增殖活性的类似物
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Application No.: US14214185Application Date: 2014-03-14
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Publication No.: US09382228B2Publication Date: 2016-07-05
- Inventor: Daniel L. Flynn , Timothy Malcolm Caldwell , Michael D. Kaufman , William C. Patt , Thiwanka Samarakoon , Lakshminarayana Vogeti , Karen M. Yates
- Applicant: Deciphera Pharmaceuticals, LLC
- Applicant Address: US KS Lawrence
- Assignee: Deciphera Pharmaceuticals, LLC
- Current Assignee: Deciphera Pharmaceuticals, LLC
- Current Assignee Address: US KS Lawrence
- Agency: Cooley LLP
- Main IPC: C07D213/65
- IPC: C07D213/65 ; C07D401/14 ; C07D405/14 ; C07D413/14 ; C07D417/14
Abstract:
Described are compounds of Formula I which find utility in the treatment of cancer, autoimmune diseases and metabolic bone disorders through inhibition of c-FMS (CSF-1R), c-KIT, and/or PDGFR kinases. These compounds also find utility in the treatment of other mammalian diseases mediated by c-FMS, c-KIT, or PDGFR kinases.
Public/Granted literature
- US20140275080A1 N-Acyl-N'-(pyridin-2-yl) Ureas and Analogs Exhibiting Anti-Cancer and Anti-Proliferative Activities Public/Granted day:2014-09-18
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