Invention Grant
- Patent Title: Buprenorphine analogs
-
Application No.: US14600501Application Date: 2015-01-20
-
Publication No.: US09382260B2Publication Date: 2016-07-05
- Inventor: R. Richard Goehring , Laykea Tafesse , Jiangchao Yao
- Applicant: Purdue Pharma L.P.
- Applicant Address: US CT Stamford
- Assignee: Purdue Pharma L.P.
- Current Assignee: Purdue Pharma L.P.
- Current Assignee Address: US CT Stamford
- Agency: Purdue Pharma L.P.
- Agent Alan L. Koller; Weiying Yang
- Main IPC: A61K31/497
- IPC: A61K31/497 ; A61K31/439 ; C07D489/12 ; C07D489/02
Abstract:
The present invention is directed to Buprenorphine Analog compounds of Formula I, II, III, IV or V and including various stereoisomers (such as Formula IA shown below), wherein R1, R3a, R3b, R16, R15, G, Q, X, A and Z are as defined herein. Compounds of the Invention may be useful for preparing medicaments useful for treating pain, constipation, and other conditions modulated by activity of opioid and ORL-1 receptors. Compounds of the Invention may be useful for treating Conditions such as pain, constipation, and others modulated by activity of opioid and ORL-1 receptors.
Public/Granted literature
- US20150203504A1 BUPRENORPHINE ANALOGS Public/Granted day:2015-07-23
Information query
IPC分类:
