Invention Grant
- Patent Title: Compositions and methods of use for therapeutic antibodies
- Patent Title (中): 用于治疗性抗体的组合物和方法
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Application No.: US13326569Application Date: 2011-12-15
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Publication No.: US09382326B2Publication Date: 2016-07-05
- Inventor: Christoph Heusser , Julia Neugebauer , Eveline Schaadt , Stefanie Urlinger , Maximilian Woisetschlaeger
- Applicant: Christoph Heusser , Julia Neugebauer , Eveline Schaadt , Stefanie Urlinger , Maximilian Woisetschlaeger
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Priority: EP08160671 20080717; EP09160326 20090515
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C07K16/28 ; A61K39/00
Abstract:
The present invention relates to antibodies that specifically bind to the BAFF receptor (BAFFR). The invention more specifically relates to specific antibodies that are BAFFR antagonists with in vivo B cell depleting activity and compositions and methods of use for said antibodies to treat pathological disorders that can be treated by killing or depleting B cells, such as systemic lupus erythematosus or rheumatoid arthritis or other autoimmune diseases or lymphomas, leukemias and myelomas.
Public/Granted literature
- US20120195913A1 COMPOSITIONS AND METHODS OF USE FOR THERAPEUTIC ANTIBODIES Public/Granted day:2012-08-02
Information query
