- Patent Title: Amino acid sequences directed against the Angiopoietin/Tie system and polypeptides comprising the same for the treatment of diseases and disorders related to angiogenesis
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Application No.: US14476802Application Date: 2014-09-04
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Publication No.: US09382333B2Publication Date: 2016-07-05
- Inventor: Maria Gonzalez Pajuelo , Michael John Scott Saunders , Johannes Joseph Wilhelmus De Haard , Peter Vanlandschoot
- Applicant: Ablynx N.V.
- Applicant Address: BE Zwijnaarde
- Assignee: Ablynx N.V.
- Current Assignee: Ablynx N.V.
- Current Assignee Address: BE Zwijnaarde
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: C12P21/08
- IPC: C12P21/08 ; C07K16/28 ; C07K16/22 ; C07K16/46
Abstract:
The present invention relates to amino acid sequences that are directed against proteins from the group of the Angiopoietin/Tie family such as Tie1, Tie2, Ang1, Ang2, Ang3, Ang4, Angptl1, Angptl2, Angptl3, Angptl4, Angptl5, Angptl6, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more of such amino acid sequences.
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