Invention Grant
- Patent Title: Induction of hemogenic endothelium from pluripotent stem cells
- Patent Title (中): 从多能干细胞诱导血液内皮细胞
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Application No.: US14058959Application Date: 2013-10-21
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Publication No.: US09382531B2Publication Date: 2016-07-05
- Inventor: Igor Slukvin , Irina Elcheva
- Applicant: Wisconsin Alumni Research Foundation
- Applicant Address: US WI Madison
- Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
- Current Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
- Current Assignee Address: US WI Madison
- Agency: Quarles & Brady, LLP
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N15/00 ; C12N5/0789 ; C12N15/11 ; C12N15/66
Abstract:
Described herein are methods and related compositions for inducing differentiation of human pluripotent stem cells (hPSCs) into hemogenic endothelium with pan-myeloid potential or restricted potential, by forced expression in the hPSCs of a combination of transcription factors as described herein.
Public/Granted literature
- US20140234971A1 Induction of Hemogenic Endothelium from Pluripotent Stem Cells Public/Granted day:2014-08-21
Information query
