Invention Grant
- Patent Title: Treatment of pyrroline-5-carboxylate reductase 1 (PYCR1) related diseases by inhibition of natural antisense transcript to PYCR1
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Application No.: US14591626Application Date: 2015-01-07
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Publication No.: US09382543B2Publication Date: 2016-07-05
- Inventor: Joseph Collard , Olga Khorkova Sherman
- Applicant: CuRNA, Inc.
- Applicant Address: US FL Miami
- Assignee: CuRNA, Inc.
- Current Assignee: CuRNA, Inc.
- Current Assignee Address: US FL Miami
- Agency: CuRNA, Inc.
- Agent Monte R. Browder
- Main IPC: C12N15/113
- IPC: C12N15/113 ; A61K31/7088 ; C12Q1/68
Abstract:
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Pyrroline-5-carboxylate reductase 1 (PYCR1), in particular, by targeting natural antisense polynucleotides of Pyrroline-5-carboxylate reductase 1 (PYCR1). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of PYCR1.
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Information query
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