Invention Grant
- Patent Title: Markers for identifying breast cancer treatment modalities
- Patent Title (中): 识别乳腺癌治疗方式的标志物
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Application No.: US13985470Application Date: 2012-02-15
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Publication No.: US09382588B2Publication Date: 2016-07-05
- Inventor: Mathieu Lupien , Luca Magnani
- Applicant: Mathieu Lupien , Luca Magnani
- Applicant Address: US NH Hanover
- Assignee: Trustees of Dartmouth College
- Current Assignee: Trustees of Dartmouth College
- Current Assignee Address: US NH Hanover
- Agency: Licata & Tyrrell P.C.
- International Application: PCT/US2012/025183 WO 20120215
- International Announcement: WO2012/112645 WO 20120823
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C07K16/30 ; G01N33/574
Abstract:
The present invention includes methods for identifying patients who will be resistant to endocrine therapy during breast cancer treatment and determining patient outcome. The methods are based on identifying increased expression of PBX1, or the cistrome signature associated therewith, in breast tissue samples.
Public/Granted literature
- US20140011695A1 MARKERS FOR IDENTIFYING BREAST CANCER TREATMENT MODALITIES Public/Granted day:2014-01-09
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