Invention Grant
US09383350B2 Engineered cell growth on polymeric films and biotechnological application thereof
有权
聚合物膜上的工程化细胞生长及其生物技术应用
- Patent Title: Engineered cell growth on polymeric films and biotechnological application thereof
- Patent Title (中): 聚合物膜上的工程化细胞生长及其生物技术应用
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Application No.: US13922432Application Date: 2013-06-20
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Publication No.: US09383350B2Publication Date: 2016-07-05
- Inventor: Kevin Kit Parker , Adam W. Feinberg , George M. Whitesides , Sergey S. Shevkoplyas , Alexander Feigel
- Applicant: President and Fellows of Harvard College
- Applicant Address: US MA Cambridge
- Assignee: President and Fellows of Harvard College
- Current Assignee: President and Fellows of Harvard College
- Current Assignee Address: US MA Cambridge
- Agency: McCarter & English, LLP
- Agent Maria Laccotripe Zacharakis; Deborah L. Nagle
- Main IPC: G01N33/50
- IPC: G01N33/50 ; C12N5/00 ; C12N5/077
Abstract:
A free-standing thin film is fabricated from a structure comprising a base layer coated with a sacrificial polymer layer, which is in turn coated with a flexible polymer layer. Cells are then seeded onto the flexible polymer layer and cultured to form a tissue. The flexible polymer layer is then released from the base layer to produce a free-standing thin film comprising the tissue on the flexible polymer layer. In one embodiment, the cells are myocytes, which can be actuated to propel or displace the free-standing film. In another embodiment, the free-standing film is used to treat injured human tissue.
Public/Granted literature
- US20140004553A1 ENGINEERED CELL GROWTH ON POLYMERIC FILMS AND BIOTECHNOLOGICAL APPLICATION THEREOF Public/Granted day:2014-01-02
Information query
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