Invention Grant
US09383352B2 Salivary protein glycosylation test for diagnosis and monitoring of diabetes
有权
唾液蛋白糖基化检测用于诊断和监测糖尿病
- Patent Title: Salivary protein glycosylation test for diagnosis and monitoring of diabetes
- Patent Title (中): 唾液蛋白糖基化检测用于诊断和监测糖尿病
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Application No.: US14226131Application Date: 2014-03-26
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Publication No.: US09383352B2Publication Date: 2016-07-05
- Inventor: Srinivasa R. Nagalla , Eric S. Bean
- Applicant: DiabetOmics, LLC
- Applicant Address: US OR Hillsboro
- Assignee: Diabetomics, Inc.
- Current Assignee: Diabetomics, Inc.
- Current Assignee Address: US OR Hillsboro
- Agency: Schwabe Williamson & Wyatt
- Main IPC: G01N33/52
- IPC: G01N33/52 ; G01N33/68 ; G01N33/66 ; G01N21/78

Abstract:
Disclosed herein are methods and tests for diagnosing and/or monitoring a metabolic condition such as diabetes in a subject, wherein the methods and tests measure salivary glycoproteins. Some of the methods are based on the oxidation of glycoproteins in a sample from the subject, such as saliva or urine, for example using sodium metaperiodate, and then detecting the aldehydes generated during oxidation using a chemical detection method. Also disclosed are kits and lateral flow devices for detecting glycoproteins in a saliva sample.
Public/Granted literature
- US20150276723A1 SALIVARY PROTEIN GLYCOSYLATION TEST FOR DIAGNOSIS AND MONITORING OF DIABETES Public/Granted day:2015-10-01
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