Invention Grant
- Patent Title: Fluorescent methods and materials for directed biomarker signal amplification
-
Application No.: US14307258Application Date: 2014-06-17
-
Publication No.: US09383353B2Publication Date: 2016-07-05
- Inventor: Brent S. Gaylord , Janice W. Hong , Tsu-Ju Fu , ChengJun Sun , Russell Baldocchi
- Applicant: Sirigen Inc.
- Applicant Address: US CA La Jolla
- Assignee: Sirigen Inc.
- Current Assignee: Sirigen Inc.
- Current Assignee Address: US CA La Jolla
- Agency: Bozicevic, Field & Francis LLP
- Agent Glen J. Foulds; Bret E. Field
- Main IPC: G01N33/533
- IPC: G01N33/533 ; G01N21/76 ; G01N33/53 ; G01N33/542 ; G01N33/58 ; C08G61/02 ; H01L51/00

Abstract:
Methods and compositions are provided that include a multichromophore and/or multichromophore complex for identifying a target biomolecule. A sensor biomolecule, for example, an antibody can be covalently linked to the multichromophore. Additionally, a signaling chromophore can be covalently linked to the multichromophore. The arrangement is such that the signaling chromophore is capable of receiving energy from the multichromophore upon excitation of the multichromophore. Since the sensor biomolecule is capable of interacting with the target biomolecule, the multichromophore and/or multichromophore complex can provide enhanced detection signals for a target biomolecule.
Public/Granted literature
- US20150309016A1 Fluorescent Methods and Materials for Directed Biomarker Signal Amplification Public/Granted day:2015-10-29
Information query
IPC分类: