Invention Grant
- Patent Title: Methods for detecting allosteric modulators of protein
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Application No.: US14548804Application Date: 2014-11-20
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Publication No.: US09383361B2Publication Date: 2016-07-05
- Inventor: Joshua S. Salafsky
- Applicant: Biodesy, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Biodesy, Inc.
- Current Assignee: Biodesy, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: G01N33/573
- IPC: G01N33/573 ; G01N33/68 ; G01N33/74
Abstract:
The present invention discloses, inter alia, methods for labeling a target protein with an SHG-active probe for detection by second harmonic or sum-frequency generation in order to identify agents which bind to an allosteric site on the target protein thereby altering its structural conformation.
Public/Granted literature
- US20150301048A1 METHODS FOR DETECTING ALLOSTERIC MODULATORS OF PROTEIN Public/Granted day:2015-10-22
Information query
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