Methods and apparatus to manage zones of a playback system are disclosed. An example method includes displaying a plurality of zone icons, including a first zone icon and a second zone icon, each of the zone icons representing zone player(s) operable to play back multimedia content in a local area network, wherein the first and second zone icons are currently located in a first zone group region, and wherein the zone players associated with the first and second zone icons are members of a first zone group, the first zone group synchronously playing back a first multimedia content; receiving a first drag and drop input to select the second zone icon and drag the second zone icon from inside the first zone group region to outside the first zone region; and, based on the first drag and drop input, causing the zone player(s) associated with the second zone icon to be disassociated with the first zone group.